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The differential impact of the number of prior lines of therapy and the setting of prior therapy (perioperative or metastatic) is unclear in advanced urothelial carcinoma.
This study was designed to examine the relationship of prior therapy, bone marrow metastases, mobilization, and blood progenitor/stem cell (BSC) collection in breast cancer patients.
I cringe when I think of the partners who told me of prior therapy with clinicians who either minimized their partner's sexual compulsivity or blamed them for it.
See Table 2 for details of prior therapy.
The safety profile of second-line axitinib and sorafenib differed modestly by duration of prior therapy.
Any number and type of prior therapy except prior MTOR inhibitors were allowed.
Clinical benefit was detected regardless of prior therapy, but no overall survival benefit has been observed.
Safety profiles differed modestly by type and duration of prior therapy.
PFS and overall survival (OS), and safety by type and duration of prior therapy were evaluated.
Type and setting of prior therapy in both arms were also prospectively recorded.
Details of prior therapy could not be extracted from trial publications.
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