Untreated or improperly treated wastewater has often been cited as the primary contamination source of groundwater.
In addition, non-specific binding of the anti-human CD31 antibody was ruled out by using fibroblasts as negative anti-C31-binding controls since fibroblasts are the main cause of primary culture contamination.
Primary contamination is caused by direct contact with the radioactive substance.
In addition to modeling for basic coverage and MAF, we also model for aneuploidy, normal/diploid contamination of primary tumor samples, mouse contamination of human tumors grown in xenograft and we perform auto-correction of systematic sequencing biases using matched normal/control samples.
We have developed a computational algorithm to detect CNV boundaries from whole-genome sequencing data and assigned digitized copy number by modeling for sample-specific confounding factor such as aneuploidy, normal/diploid contamination of primary tumors and mouse contamination in xenograft models.
We analyzed the prevalence and bacteriology of intraoperative contamination of primary joint replacement and assessed whether its presence is related to periprosthetic joint infection (PJI) on long-term follow-up.
Normal/diploid cell contamination of primary tumors complicates CNV calling by diluting signal from the tumor cells and reducing the amount of observed coverage separating copy number levels as well as altering the expected minor allele frequencies at each copy number level.
Although the sources of contamination are of primary importance for drinking water quality, other climatic and locality factors may also influence the bacterial contamination rates in open water sources.
Two authors (SS and HS) independently assessed risk of bias using standard Cochrane criteria, including sequence generation, allocation concealment, blinding, protection against contamination, reliability of primary outcomes, follow up of patients, and performance of baseline measurement.
Two reports mentioned evidence of cross-contamination from a primary contaminated object to another object or site.
