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To assess the possibility of a causal link at the cellular level, we analyzed single-neuronal activity patterns in the ACC both during an ongoing behavioral trial and as a function of previous trial performance in monkeys trained to execute this highly attention-demanding task.
The factor of previous trial (correct/incorrect) was added as another factor, and mean RTs were calculated per condition.
The Hokusai-VTE study of edoxaban is the most recent study and aimed to address some weaknesses of previous trial designs.
Specifically, we explored how intentional binding and explicit prediction of action outcomes varied as a function of the nature and length of previous trial runs.
While the elephant was away from the gate with the zookeeper, the experimenter recorded the result of previous trial then set up the next trial out of the elephant's sight.
Nevertheless, as we previously reported that the wait-start latency was influenced by previous trial reward history (Donnelly et al., 2014), the behavioural consequences of previous trial outcomes have been included in the present analysis.
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Analysis of previous trials has shown that H+ISDN appears especially beneficial in African American patients.
Furthermore, the restrictive criteria of previous trials excluded most patients treated in daily practice.
Nonetheless, results of previous trials assessing the role of distal protection during primary PCI have been controversial.
Temporal integration requirements were manipulated by varying, across conditions, the window of previous trials over which the reward function was calculated.
But continuing WISDOM would have been ethically questionable, given the results of previous trials, says Elizabeth Barrett-Cofnor of the University of California, San Diego--and the heightened risks would have made recruiting participants even more difficult.
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