Exact(2)
For analyses of potential intermediaries, models were restricted to the 2,949 participants with complete data on the covariates considered.
Given the complex interplay between components of the immune system, metabolic factors, CMV and ageing, as well as the contribution of potential intermediaries such as oxidative stress and inflammation to these processes, bidirectional or cyclical relationships between these factors cannot be ruled out.
Similar(6)
Relative to participants without diabetes, those with any diabetes had an elevated risk of hospitalization for an injurious fall (hazard ratio [HR] 1.48 [95% CI 1.12 1.95]) (Table 2), even after adjustment for potential intermediaries (history of fainting, standing balance score, cystatin C level for renal function, and number of prescription medications) (1.41 [1.41–1.41]).
Additional adjustment for potential intermediaries, such as fainting in the past year, standing balance score, cystatin C level, and number of prescription medications, accounted for some of the increased risk associated with diabetes (1.41 [1.05–1.88]) and insulin-treated diabetes (2.24 [1.2.24.03]).
Models assessing potential intermediaries were limited to participants with baseline data on all of these variables (N = 2,949).
Our study allows the investigation of specific miRNA:mRNA interactions based on anti-correlated expression, and allows us to focus on known oxidative stress and cytoskeletal pathway mRNAs as attractive potential intermediaries between miRNAs and phenotypes.
Actinobacillus succinogenes naturally produces high concentrations of succinate, a potential intermediary feedstock for bulk chemical productions.
Main concerns: 1) The inclusion of the zona incerta as a potential intermediary of the cortical inhibition at 10 Hz provides a potential mechanism and it is valuable.
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