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It was introduced in February 2004 as a clinical test coupled with FISH confirmation of potential imbalances ascertained after screening by CMA [24] (http://www.bcm.edu/cma/).edu/cma/
We attempted, therefore, to reduce the impact of potential imbalances by adjusting for age, severity of illness and use of drotrecogin alfa.
We compared the distribution of patients and tumor characteristics and treatment according to EGFR expression (staining intensity and extent) to assess the presence of potential imbalances in the known prognostic variables.
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Also, looking ahead to the next 12 months, we are wary of potential imbalance in supply and demand, as the company ramps 300 mm production".
That design requires for a thorough investigation of potential imbalance of confounding factors between groups, as discussed above, but the design may have the benefit of avoiding the impact of the data collection per se on reported emesis.
Furthermore, some have advocated for the use of regression adjustment to estimate the effect of treatment after adjusting for potential imbalances in prognostically important baseline covariates between treatment groups.
The difference in global response between groups remained significant after adjustment for potential imbalances, including duration of treatment and central line status [ 3].
Adjustment made using aggregate values will not account for potential imbalances between study arms resulting from the lack of randomisation.
14 The results of the sensitivity analyses showed that our results were robust to a wide range of assumptions about potential imbalances of the distribution of patients with poor functional status among the two study groups.
The previously mentioned MFA studies focused on quantifying flows of critical metals and potential imbalances between co-products of mining, but are lacking a clear link to models of total available resources and mining capacity.
We used differences between groups identified by assessment of RR to identify any potential imbalances in the occurrence of specific AEs between the 2 groups.
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