Sentence examples for of potent activity from inspiring English sources

A key test of any new class of antiretroviral drug is a demonstration of potent activity against HIV-1 with known drug-resistance mutations.

However, the mechanism of potent activity of AEMPs in FBS is not clear at this point.

Compared with other biguanides, metformin expresses the best balance of potent activity and low toxicity.

Compounds 1– 4, 6, 7, and 10– 12 are examples of the closely related analogues which exhibit similar levels of potent activity (IC50 0.034–0.20 μM, Table 1).

Hock fragmentation would not produce cytotoxic carbon radicals, and thus the observation of potent activity by 9 (and 13) suggests action via the canonical mechanism of trioxolane toxicity (Scheme 1).

Although a QSAR formalism cannot be applied to predict the potency of such compounds, they can be easily selected from SARMs containing activity cliffs on the basis of a "guilt-by-association" principle, i.e., VCs are preferentially selected that are neighbors of potent activity cliff partners.

Consequently, cytotoxic agents pose as candidates as for antiangiogenic agents on top of their potent activity in causing death of cancerous cells.

Consequently, cytotoxic agents pose as candidates as antiangiogenic agents on top of their potent activity in causing death of cancerous cells.

The importance of FALDH has been greatly increased by the discovery of its potent activity toward S-nitrosoglutathione, the condensation product of glutathione and nitric oxide (NO) [ 3- 5].

One class of chemopreventive agents, 1,2-dithiole-3-thiones, was developed on the basis of their potent activity in rodent tissues as inducers of GSTs.

Antibody drug conjugates represent a promising new class of anticancer therapeutics that combine the specificity of an antibody with the potent activity of cytotoxic drugs.