In multiple-dimensional or graph data, whose sensitivity is so high that it may lead to poor utility of the data, how the sensitivity of function can be reduced and the utility enhanced.
Whether branches 1 and 5 were included or not, PBS analyses give the rough appearance of relatively superior performance of ND5, ND4, CYTB, 16SrRNA, and ND2 genes, and on the other hand, of the poor utility of ND3, ND4L and ND1 genes.
Part of the complexity of PC screening is the poor utility of PSA, as around two thirds of men with an elevated PSA will not have cancer diagnosed on biopsy and lower values of PSA cannot exclude the presence of cancer [ 18].
The low prior probability of SBI in this population explains the apparently high negative predictive values of many variables, reflected in the poor utility of most negative likelihood ratios.
It is possible therefore that the relatively poor utility of ERβ2 protein assessment by immunostaining as a measure of outcome prediction may be due to high levels of ERβ2 protein in some cases (with lower levels of ERβ2 mRNA) being related to some form of protein stabilization, or detection of inactive ERβ2.
Substantial floor and ceiling effects for SF-36 scores were previously reported in other investigations [ 2, 40], further indicating poor utility of SF-36 in orthopedics.
This result is not surprising, given that several other plant studies have reported poor utility of the core DNA barcodes at lower taxonomic level especially among closely related species and in taxa characterized by recent rapid radiation and hybridization.
If positive, a tourniquet test might have allowed classification as DHF rather than dengue fever in 357 additional cases, but several studies have demonstrated poor utility of the test in clinical practice, and it is infrequently performed in Vietnam [ 25, 27].
The poor utility for detection of N deficiencies was well known from the literature, although not recognized by many.
In receiver operating characteristic (ROC) curve analysis, donor urine NGAL had poor utility for prediction of DGF (area under the curve 0.595) or prolonged DGF (area under the curve 0.616).
