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It is important, therefore, to be able to precisely localize sites of persistent disease.
The detection of hTERT expression was significantly associated with the presence of persistent disease (P =.035).
Both telomerase activity and hTERT expression were detected in all 6 cases of persistent disease on the initial molar tissue sampled.
Conclusions: Compared with telomerase activity, the expression of hTERT is significantly associated with the development of persistent disease in complete hydatidiform moles.
This Phase I study was designed to evaluate the tolerability of involved-field radiotherapy (IFRT) to areas of persistent disease in patients with high-risk Hodgkin's disease and non-Hodgkin's lymphomas before autologous stem cell transplantation (ASCT).
Objective: This study was undertaken to determine the putative role of telomerase activity and human telomerase reverse transcriptase (hTERT) expression in the development of persistent disease in patients with a diagnosis of complete hydatidiform mole.
Similar(19)
They had good overall performance, with a sufficiently high AUC and good performance of the proposed cut-point of 6 for persistent disease, which could be considered RA.
Presence of ≥2 erosive joints showed a positive predictive value for RA development of 53% and for persistent disease of 68%.
Inhaled forms such as beclomethasone are usually used except in the case of severe persistent disease, in which oral corticosteroids may be needed.
Meanwhile, CT-based 3D treatment planning obtained excellent visualization of the persistent disease and normal structures.
For 3D-BT,the GTV was determined by a radiation oncologist as the macroscopic extent of the persistent disease area, the CTV included the persistent disease area and the nasopharyngeal primary tumor area.
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