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Dozens of other feedback cycles will be disrupted.
We have determined the effects of control by overall feedback inhibition on the systemic behavior of unbranched metabolic pathways with an arbitrary pattern of other feedback inhibitions by using a recently developed numerical generalization of Mathematically Controlled Comparisons, a method for comparing the function of alternative molecular designs.
Answering these questions will probably require analysis of the larger p53 pathway beyond the p53-Mdm2 negative feedback loop, so as to obtain knowledge of other feedback structures in the p53 regulatory pathway, such as those involved in damage sensing, p53 upregulation, and modification.
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Moreover, no studies had directly tested the role of the other feedback pathway to the neocortex, so its role in adaptation remained unclear.
Of course, other feedback inhibitors that show cyclic expression in the PSM, including Sprouty2 and Dusp4, are also candidates for this putative mediator activity.
The response of different strains of mice and the role of serotonin or other feedback mechanisms are unclear.
Anyone is permitted, even encouraged, to submit bug reports, wish lists of features and other feedback via the Web site.
Languages: Annual report by Dossier Review Committee to department on state of Sight and Prepared translations; other feedback to be given by judges of the Sight Translation Competition.
The night before, while naked in Doug's bed, we'd decided to give each other feedback ahead of time.
Twelve participants learn the nuts and bolts of good writing, give each other feedback on their stories and essays, work on revisions, and take part in writing exercises.
On this basis, Sprouty interactions with other feedback regulators of the two pathways and its significance in prostate cancer tumorigenesis and progression have been explored by some investigators.
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CEO of Professional Science Editing for Scientists @ prosciediting.com