At present, they fall short of optimal standards.
Probable causes for such conflict could be the unavailability of an optimal, standard therapy for this disease, to which a comparison of bevacizumab would facilitate more accurate data [ 11].
An analogous system was developed by the European Vasculitis Study Group to include both GPA and MPA (Table 2) [ 25] in order to define eligibility for a sequence of randomised controlled trials aimed at defining the optimal standard of care.
But when it comes to clinical advice and treatment, how do patients know what the optimal standard of care looks, sounds and feels like?
As such, integration of biobehavioral management with pharmacological interventions in a multidisciplinary treatment approach is regarded as the optimal standard of care for pediatric migraine [6, 7].
[ 31] Industrialised societies expect to receive an optimal standard of medical care.
The national guidelines for Type 2 diabetes care in the community were used to define the optimal standard of care in Ireland [ 7].
From an individual patient's perspective, the results of this article suggest that the 12 month cut-off for dual antiplatelet therapy should not necessarily be considered as the optimal standard of care choice.
The source of infection has been controlled and optimal standard care (including adequate antimicrobials and failing organ support) has been initiated, but the expected effects of this strategy are either delayed (>12 24 hours) or unpredictable.
