Sentence examples for of numerous signalling pathways from inspiring English sources

Aberrant activation of numerous signalling pathways has been observed in human EOC that result in stimulated proliferation or dysregulated cell death and most have been reviewed elsewhere.

These studies underscore the involvement of numerous signalling pathways in ERα-regulated breast cancer cell growth and suggest novel targets to improve the efficacy of anti-oestrogen therapy.

From this understanding of autophagy as a dynamic integrator of numerous signalling pathways, it is evident that disruptions in the functionality of other pathways are likely to disrupt autophagy and therefore cellular homeostasis.

In animals, Mediator has been implicated in the control of differentiation and morphogenesis through modulation of numerous signaling pathways.

Interaction of numerous signaling pathways in endothelial and mesangial cells results in exquisite control of the process of physiological angiogenesis, with a central role played by vascular endothelial growth factor receptor 2 (VEGFR-2) and its cognate ligands.

Our 3D TF activity array profiled the activity of numerous signaling pathways simultaneously as cells organized into structures and responded to biochemical stimuli.

S-nitrosylaton is implicated in the regulation of numerous signaling pathways with a diversity of regulatory roles.

Primary cilia are ubiquitous organelles that serve as a cellular hub for the transduction of numerous signaling pathways.

Cancer metastasis is a multi-faceted process requiring the disregulation of numerous signaling pathways, including those associated with cell adhesion and motility.

The present review will discuss β-catenin as a central transducer of numerous signaling pathways and its role in mammary development and breast cancer.

Despite the activation of numerous signaling pathways, STAT5 is mainly a BCR-ABL substrate and is persistently phosphorylated in CML cells [ 10].