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The same postholes may have been reused multiple times for multiple replacements of the same house (Fig. 7).
It would be interesting to verify if multiple replacements of discriminating R1, R2 and R3 HyPRE elements by PRAC specific residues would induce any changes in substrate specificity.
The tube carries the first mirror (M1) with a shutter and allows multiple replacements of M1.
Because none of the replacements acted as a switch that impaired binding to some sequences while improving affinity for others, multiple replacements were necessary to achieve the derived specificity and affinity.
After confirmation of multiple faulty replacement devices came in over the weekend, however, the stock has dropped almost 10% in the past two days, to 1,554,000 won.
The use of such high standards in the management of replacement animals mitigates the risk associated with using multiple replacement sources.
The use of multiple sources for replacement animals may be a necessity created by modern pork production systems, in order to facilitate improvements in the breeding program; the strategy described above mitigates the risk posed by this practice.
Given the rarity of multiple substitutions, these double replacements are plausible RCGs (RGC_CAMs).
It is also of interest that against the background of multiple fixations of atypical replacements in paralogs D2 and D1, such events were not observed for D3 evolution.
The α/β-peptides we have examined retain the side chain sequence of the α-peptide that inspired them, but the presence of multiple α → β replacements is seen to block recognition by polyclonal antibodies that bind strongly to the parent α-peptide or to prevent participation in a TCR + MHC I + peptide complex that accommodates the parent α-peptide epitope.
The opportunistic replacement of multiple Life-Limited Parts (LLPs) is a problem widely existing in industry.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com