Sentence examples for of multiple reads from inspiring English sources

The breakpoint-FRC examines the presence of multiple reads that share a common breakpoint, which often indicate assembly problems.

In order to determine which sequences to designate as novel miRNAs, we screened the set of novel hairpin-derived small RNAs using criteria similar to those used in other recent miRNA discovery studies [23], [33], [36]: i. pairing characteristics of the hairpin, ii. the presence of multiple reads sharing the same 5' terminus, iii.

When using barcode tags, consensus sequences of multiple reads from individual molecules were analysed.

Error rates can be further reduced from these levels by taking a consensus of multiple reads.

Assembling reads into contigs allows the program to identify repetitive sequences that span the length of multiple reads.

That the alignments spanned the length of multiple reads suggests that these contigs were correctly assembled rather than artificial hybrid sequences.

Furthermore, we see some indication of correlations in the occurrence of multiple read errors.

However, this also necessitates the identification of multiple read pairs that are induced by the same tandem duplication.

Another recently introduced parameter for the quality assessment of multiple read alignments is the variance of the ratio of reads that support the alternate allele at heterozygous positions [ 14].

Fragmentation at random nucleotide locations is an essential component of library construction for the various short-read sequencing instruments [ 1], through delivery of multiple read initiation points in template molecules.

Our method then groups the RF read pairs that are likely to be induced by the same tandem duplication and uses the information extracted out of multiple read pairs along with the empirical fragment length distribution to precisely infer the putative breakpoints of the tandem duplications.