Thus, although bioassays remain the indispensable mainstay of most large-scale resistance monitoring programs, much attention is being paid to developing more incisive techniques that not only offer greater precision and turnover rates but also diagnose the type of mechanism present and, the genotypes of resistant insects.
There is disagreement among evolutionary biologists as to whether population- or species-level processes predominate in the creation of most large-scale trends (Gould 1988, 2002; Maurer et al. 1992; Hallam 1998), but it is worth considering the various possible causes that have been proposed.
There is little of the drawn-out negotiating with government bureaucrats that is typical of most large-scale developments.
In comparison, the concordance of most large-scale array vs. PCR comparisons [29], [30] is ∼60%, clearly demonstrating the quality of our aCGH data.
The focus of most large-scale cancer sequencing projects to date has been on finding mutations in coding regions, with the majority of sequencing projects focusing on transcript sequence.
Apart from isolated exceptions where a negative exponential-law was found to be a better fit [ 30], the node-degree distributions of most large-scale coexpression networks built for organisms as different as Saccharomyces cerevisiae [ 31, 32], mice [ 33] and human [ 33- 35] and diseased states like gastric cancer [ 36], have been found to follow a negative power law.
Clinical referrals following face-to-face feedback of results to participants 3 to 6 weeks after their initial visit are an important and unique feature of the Qatar Biobank; such referrals have not been included in the protocol of most large-scale population based prospective studies.
Like most large-scale collectors of early Italian art, the Stoclets picked up some fakes here and there, including a small "Maestà" that they thought was by Duccio.
Epidemiologist Sarah Medland of the Queensland Institute of Medical Research in Australia adds another note of caution: Most large-scale genetic studies replicate their findings using preexisting sets of data, Medland says, but "There was no replication here".
Ai Weiwei, the provocative Chinese artist, will build more than 100 fences and installations around New York City this fall for "Good Fences Make Good Neighbors," one of his most large-scale public art projects to date.
Due to the well-known curses of dimensionality most large-scale stochastic optimization problems cannot be solved to optimality.
