Sentence examples for of lymphocyte surface from inspiring English sources
The mPEG-modified T cells resulted in significant immunocamouflage of lymphocyte surface proteins and decreased interactions with APC.
Loss of lymphocyte surface Trx-1 may be a useful biomarker of healthy ageing.
The results of lymphocyte surface marker analysis performed in 15 patients are summarized in Table 3.
The present study was performed to clarify: what is the expression profile of lymphocyte surface markers in polytraumatized patients over time; and are there differences in the expression patterns of polytraumatized patients compared with healthy controls and with patients with severe sepsis and septic shock?
Analyses of lymphocyte subpopulations were performed on unfixed cell preparations with a fluorescence activated cell sorter (FACScan, Becton-Dickinson FACS Systems, Sunnyvale, California) and a panel of monoclonal antibodies (mAbs) to lymphocyte surface antigens (Ortho Diagnostic Systems: OKT3, OKT4, OKT8, OK-NK, OKB20, OKT26a, OK-DR; Thermo-Scientific, Rockford, IL, USA: TcRδ1 and δTcS1).
How the IgD and IgM islands are kept apart on resting cells and are joined together on activated B cell is not known at present and shows that much remains to be learned about the nanoscale organization of the lymphocyte surface and its reorganization upon the activation of these cells.
When lymphocytes were exposed to increasing quantities of a monoclonal antibody raised against the extracellular portion of CD45, a transmembrane protein tyrosine phosphatase covering over 10% of the lymphocyte surface, T. evansi membrane extracts showed a dose-dependent decrease in cytotoxicity.
Similarly, increased mRNA levels of the lymphocyte surface marker CTLA4 is possibly due to the presence of larger numbers of T cells in MDV infected birds as a result of higher levels of infection.
The success of rituximab and the identification of other CLL lymphocyte surface antigens have spurred the development of a multitude of monoclonal antibodies targeting distinct proteins and epitopes in an attempt to target CLL cells more effectively.
The engagement of PD1 on the lymphocyte surface by one of its ligands, PD-L1, that can be expressed on melanoma cells, delivers inhibitory signals resulting in T-cell function down-regulation [3].
Figure S6 (available on the Blood website; see the Supplemental Materials link at the top of the online article) shows FACS analysis of lymphocyte cell-surface labeling.
