Sentence examples for of lower trial from inspiring English sources

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It is also true that India's higher courts routinely revoke orders of lower trial courts.

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Before starting the review we hypothesised that several features of trial design might affect the outcome of cholesterol lowering trials of statins.

"Among people treated with evolocumab, the average LDL after one year of treatment was 48 milligrams per deciliter of blood, the lowest LDL ever seen in the experimental arm of a lipid-lowering trial," Dr. Marc Sabatine, professor medicine at Harvard-affiliated Brigham and Women's Hospital, told me.

At least one outcomes study looking into CV end points with exenatide once weekly is currently in progress (Exenatide Study of Cardiovascular Event Lowering Trial [EXSCEL], NCT01144338) and is estimated to be completed in March 2018.

The Exenatide Study of Cardiovascular Event Lowering Trial: A Randomized, Placebo-Controlled Clinical Trial to Evaluate Cardiovascular Outcomes after Treatment with ExQW in Patients with T2DM (EXSCEL, NCT01144338) will test major adverse cardiovascular outcomes including heart failure in 9,500 patients and is expected to announce the outcomes in April 2018.

Nephrology needs novel therapeutic approaches for unmet needs, and these can only be developed by a precise and detailed understanding of pathophysiological events, the evaluation of preclinical models relevant to the human situation and the improved design of lower cost clinical trials.

Ohmann et al. [ 1] found that only 25% of 225 visitors interviewed at a German University accepted taking part in clinical trials, with a likelihood of lower participation in surgical trials than in dental or pharmaceutical trials.

aWe are in no way claiming that phase IV trials are absolutely of lower risk than earlier trials for the following reasons.

Although homocysteine has consistently shown to predict cardiovascular disease in prospective studies, recent meta-analyses and reviews of the homocysteine-lowering trials showed no effect on cardiovascular end points of homocysteine lowering by means of folate and vitamin B in individuals with prior cardiovascular disease [26], [27].

We also assessed the effect of trial quality on outcome, as it is often hypothesized that, compared with trials of higher methodological quality, trials of lower methodological quality tend to yield more positive clinical signals for the therapy being tested.

Thirdly, trials using surrogate outcomes may be of lower methodological quality than trials using final patient relevant outcomes and therefore more prone to exaggeration of effect size.

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