The total RNA of liver samples was isolated using the Trizol Kit (Promega, USA).
The major ions contributing to the group separation of liver samples were phosphatidylcholines.
Additionally, ultrastructural evaluation of liver samples by electron microscopy is an important diagnostic component of hepatic dysfunction caused by metabolic abnormalities.
Three infants diagnosed with mtDNA depletion syndrome at The Children's Hospital of Philadelphia were identified, and their clinical presentation, disease course, and histologic and ultrastructural features of liver samples (pre- and postmortem) were characterized.
The basic functionality of the automatic laser control was successfully demonstrated with laser ablation experiments of liver samples using irradiation parameters close to typical clinical values.
Whole genome transcriptomic analysis of liver samples of F1 generation zebrafish exposed to 0.01 μg/L and 1 μg/L 5-FU revealed dose-dependent increases in the number of differentially expressed genes, including up-regulation of several DNA-damage-responsive genes and oncogenes (i.e., jun, myca).
Transmission electron microscopic observations of liver samples confirmed changes forall treated groups in relation to glycogen dispersion or appearance in lakes,increase of residual bodies and enlargement of cristae in mitochondria(Figure 2, panels 2 to 4).
Toxicological tests of liver samples taken from the carcass of a western gray squirrel discovered at Griffith Park a year ago found evidence of exposure to rodenticide.
Therefore, to determine whether this pathway is dysfunctional in Alzheimer's disease, we examined the lipid composition of liver samples from 14 patients and 9 control subjects, who displayed no histological sign of liver pathology.
MT: performed pathological analysis of liver samples.
The rest of liver samples were stored at -80°C.
