Once a promoter CGI is aberrantly methylated, it leads to permanent aberrant silencing of its downstream gene.
The activation of its downstream signaling pathway was investigated by Western blot analysis.
Then, we examined the role of CD146 in β-catenin activation and the expression of its downstream effectors.
We studied the dopamine (DA) D1 receptor gene and one of its downstream targets, the transcription factor c-Fos.
Each valve is under the control of its downstream pressure and closed by the upstream gas pressure.
Expression of Hnf4a and many of its downstream target genes were significantly increased in RWV cultures as compared to TCD.
Marathon Oil said Thursday its board has approved the spinoff of its downstream business to create two independent companies.
The expressed BMP2 protein was quantified by ELISA analysis (A), and the activation of its downstream Smad1/5/8 signaling pathway was studied through Western blot assay (B).
Furthermore, the reduction of Pax7, or the exogenous addition of its downstream targets, like MyoD, reversed muscle wasting by restoring cell differentiation and fusion, under tumor conditions.
Up-regulation of FXYD6 not only positively correlates with the increase of Na+/K+-ATPase but also coordinates with the activation of its downstream Src-ERK signaling pathway.
Deacetylation of TFEB enhances its transcriptional induction of its downstream target genes closely associated with lysomomal biogenesis, which eventually upregulates microglial capability in degradation of fAβ.
