Sentence examples for of interim data from inspiring English sources

However, a recommendation for SSR made with knowledge of interim data introduces bias to the trial.

The DSMB oversees implementation of the trial and monitors the safety and efficacy of interventions during quarterly reviews of interim data.

Importantly, adaptations (or changes) should not be ad hoc, but by design, based on prospectively planned, prespecified analyses of interim data.

In 27 of the 28 trials that were judged to be open to bias, some form of SSR was recommended subsequent to the review of interim data.

Independent double data extraction (M.C., P.T). was performed on all trials considered to have "extended" use of interim data or DMC recommendations.

The role of the DMEC is to consider the need for interim analyses of trial data, the implications of such analyses, and requests for release of interim data.

In February 2011, based on interim data as of October 2010 from 219 patients, the DMC recommended that all patients discontinue study treatment.

Because the DMC recommended early discontinuation of the study drug based on interim data, thereby decreasing the study's statistical power, additional study conclusions are limited.

This committee, in light of the interim data, and of any advice or evidence they wish to request, will advise the TSC if there is proof beyond reasonable doubt that one treatment strategy is better.

In six trials where SSR was recommended, the authors make reference to the use of masked interim data [ 13, 15, 16, 19- 21].

The DMEC in light of this interim data will make their recommendations to the Trial Steering Committee who will in turn decide whether the trial can continue to Stage C.