This should help policy makers, clinicians, researchers, and guideline developers to judge the applicability of individual trials and systematic reviews.
Significant heterogeneity was present between trials; therefore, we interpreted trends from visual inspection of individual trials and pooled estimates.
I also suggested that a synthesis of individual trials could lead to the largest usual-care window with which screening has the designed effect.
Also, a framework is proposed to combine DMP algorithm and hierarchical clustering to derive an optimal clustering results through a large amount of individual trials of the DMP algorithm.
In this communication, a new plan will be proposed for the conductance of rofecoxib [Vioxx] trials because the current system of individual trials is considered to be irretrievably flawed and grossly unfair.
A systematic review of the literature will fail to provide information needed for evidence-based medicine (EBM) if the design, execution and reporting of individual trials do not adhere to strict guidelines.
By its design the network allows prospective comparisons and validations of specific treatment strategies across the trials, and treatments superior beyond the limits of individual trials can be identified.
Although only a handful of drugs tested in hundreds of individual trials have improved survival, patients who receive a diagnosis of advanced breast cancer today live on average about two or more years longer than 30 years ago.
While analyses of individual trials comparing several provenances can inform us of those differences among populations that are shaped by genetics, only information gleaned from multiple trials covering an entire species range allow us to assess the relative importance of genetics and phenotypic plasticity, and how the two interact, for species survival under a changing climate1,2,3,4.
Thereby the randomized nature of individual trials is compromised.
"UPS adopted this policy without ever investigating whether it was necessary". The ruling sends the classaction case back to federal district court for a series of individual trials over compensation, which could include giving hearing-impaired employees priority for promotions into driving jobs, as well as lost wages and punitive damages.
