Sentence examples for of imprinting that from inspiring English sources

For example, loss of imprinting that leads to enhanced expression of the insulin-like growth factor 2 (isfrequentlyquently observed during cancer progression [5], [6].

We therefore believe that it is unlikely that the imprinting-related enhancement of mean response magnitude to ANOVIS was anomalous but rather interpret the effect tentatively as a result of imprinting that may reveal important details regarding the function of IMM neurons; namely the detection of incongruous auditory accompaniments to the visual imprinting stimulus.

Specifically, we focus on triples (contacts involving three loci) involving the IGF2-H19 locus, which is a classic example of imprinting that leads to allele-specific gene expression and regulation in both mouse and human [ 21- 24].

Thus, although both imprinting and inbreeding introduce a covariance between additive and dominance effects, it is only the presence of imprinting that allows the covariance in one sex to be positive.

Because of imprinting that silences the maternally inherited allele, Magel2-null mice retain expression only from the paternally inherited lacZ knock-in allele [13].

These observations demonstrate that SYT-SSX1 can induce loss of imprinting in cells that show an intact imprinted status at the H19/IGF2 locus.

Mice that inherit the gene-targeted allele from their fathers are "Magel2-null" and lack expression of Magel2 because of genomic imprinting that silences the maternally inherited wild-type allele.

Our findings suggest that marsupials use multiple epigenetic mechanisms for imprinting and support the concept that lineage-specific selective forces can produce sets of imprinted genes that differ between metatherian and eutherian lines.

Interestingly, promoters in the HCC signature included a number of imprinted genes that were consistently hypomethylated in HCC relative to surrounding tissue (GABRA5, GABRG3, HBII-52, MEST, MKRN3, TRPM5, and ZIM3).

Phenotype differences between the F <img src="http://journals.plos.org/plosone/article/asset?id=info?doi/10.1371/journal.pone.0011396.e184.PNG" class= inline-graphic"/> crosses further support possible existence of imprinted genes that affect HALI.

Placental growth is under the control of imprinted genes that may up- or down-regulate growth depending on the parent of origin.