Sentence examples for of host lymphocytes from inspiring English sources

Our study examined whether colon adenocarcinoma cells release sFasL, and induce apoptosis of host lymphocytes without direct cell cell contact.

Expression of membrane-bound Fas ligand (mFasL) on colon cancer cells serves as a potential mechanism to inhibit host immune function by inducing apoptosis of host lymphocytes.

These findings suggest that mFasL-positive colon cancer cells release sFasL, and thus may induce apoptosis of host lymphocytes as a potential mechanism for immune evasion.

Furthermore, elimination of host lymphocytes reduces the risk of host-mediated immune responses against the engineered cells that could lead to rejection, especially if encoded receptors or other transgenes include non-human or novel protein sequences.

From previous experiments and mouse models, it became apparent that prior depletion of host lymphocytes greatly improved the in vivo survival of the infused TILs, and a short in vitro culture time was important for survival, in vivo expansion and efficacy.

Fites et al. (2013) provided the first evidence for this hypothesis, demonstrating Bd inhibition of host lymphocyte proliferation.

Although a dilution factor could explain these findings, we fail to demonstrate a decrease of host lymphocyte alloreactivity on day zero which would be an efficient way to prove the effectiveness of this approach.

Survival of autoreactive host lymphocytes with persistence of autoantibody titres after autologous HSCT has been described after both myeloablative and nonmyeloablative conditioning.

In contrast, Theileria parva promotes uncontrolled proliferation of infected host lymphocytes [ 53].

The pathophysiology of HPS associated with non-viral agents may be related to the production of high levels of activating cytokines by host lymphocytes and monocytes.

This difference in the PBL cell composition may represent recruitment of host cytotoxic lymphocytes for the destruction of infected monocytes in the control of M. bovis infection [ 3, 65].