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This study has led to the development of highly efficacious fluorine-containing benzimidazoles as potential drug candidates.
Power calculations suggest a chronic HCV infection rate of at least 12/100 py (primary HCV infection rate 16/100 py) will be required for stand-alone trials of highly efficacious candidates designed to prevent chronic infection.
Incandescent lightings with deployed halogen bulbs provided an instantaneous source of highly efficacious illumination which is brighter than the drivers' ambient lights (both daylight, electrical lights and their reflections), which can help drivers get access to enough warning and help them initiate traffic safety warning as necessary.
Together, these attributes make polyanhydride particles an attractive platform for development of highly efficacious vaccines.
This is the case for all transmission settings and for all events averted, except in the case of highly efficacious BSV combined with MSTBV at very high transmission.
Probably, the effect on transmission of highly efficacious BSV, (Figure 1b, d, f) is less important for averting disease and death than is the case for PEV.
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Because of the highly efficacious immunosuppressive therapy, biopsy-proven acute rejection of histological grades 2 and higher was rare among the included patients.
Both these factors contribute to the exclusive specificity of RIT targeting viral antigens conferring the development of a highly efficacious, minimally toxic treatment modality.
Considering our results in light of these concerns, further study of the feasibility, safety, and cost-effectiveness of IPT targeted at schoolchildren with DP in different transmission settings will be warranted, but nonetheless, implementation of this highly efficacious intervention in the near future is worthy of strong consideration.
Here, we report the discovery and detailed characterization of a highly efficacious and selective FAAH inhibitor, PF-3845.
Border row management in which applications are directed from the perimeter into the block should be considered as a first directed spray of a highly efficacious insecticide.
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CEO of Professional Science Editing for Scientists @ prosciediting.com