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As Oscar Wilde put it, "all bad poetry springs from genuine feeling," meaning that the act of high expression actually means disguising those feelings we hope to express.
Some reports have suggested that the frequency of high expression human epidermal growth factor 2 (HER2) is low [9 11].
Low expression is the complement of high expression.
Promoters of high expression, actively transcribed PK genes were enriched with GC-rich motifs.
An ideal clinical outcome of high expression and less downregulation was found for two haplotypes.
Likewise, the caudal and rostral limits of high expression each lined up to form a strip of activation across the three brain subdivisions: St, N, and MV.
DME search revealed a number of motifs ranging from 6 to 10 nt which were significantly over-represented in promoters of high expression PK genes.
Primary transcripts and introns of high expression genes were significantly shorter than primary transcripts and introns of low expression PK genes (p<0.05).
Our study provides evidence of high expression of proteins involved in the glyoxylate cycle, for the first time directly implicating its importance in EBPR metabolism.
Interestingly, we were able to consistently detect an association of menin along the length of the locus under conditions of high expression.
This is surprising, given that common codons are an indicator of high expression [6], which should be negatively affected by a rare codon cluster [3].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com