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(b) Experimental validation by RT-PCR analysis of a selected set of high confident skipped exonic events reveals that selected mRNA isoforms with skipped events are more abundant during embryonic and perinatal stages.
Firstly, we applied the generally accepted Bayesian criterion, Opost=1, to define the cutoff of high confident interactive pairs.
Overall the total number of high confident annotated RNAs has correspondingly changed from 3,556 to 3,539.
Here we adopt the cutoffs used for cow in the tRNAscan-SE database to gain a set of high confident tRNA candidates (See Methods section for details).
All pairs of high confident annotations less than 10,000 nt apart on the same strand, were used to form clusters by single linkage.
Thus, the number of high confident annotated snoRNAs is now changed from 638 to 621, in which the subset of curated snoRNAs now consist of 289 compared to the previous 269.
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Stress did not influence emotion perception or the extent of high-confident errors, but patients with schizophrenia showed an increase in high-confident emotion perception errors conditional on higher arousal.
A set of high-confident biomarkers from cardiovascular-related network were identified as candidate network biomarkers and used to classify two groups of patients more accurately than current single ones without consideration of biological molecular interaction [19].
(B ) Schema retrieval: left, % of correct responses; middle, average reaction time (s); right, % of high-confident ratings (i.e. "sure -responses).
To find primary initial protein phosphorylation inducers, we submitted the flanking sequences of high-confident phosphorylation residues to Motif-X.
(A ) Data represents the % of correct responses, (B ) the average reaction time (s), and (C ) the % of high-confident ratings (i.e. "sure -responses).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com