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Moreover, Met-RANTES treatment significantly protected T. cruzi-infected mice against connexin 43 loss in heart tissue and CK-MB level enhancement, markers of heart dysfunction.
Six weeks later, SPRC-treated rats showed a significant alleviation in the development of heart dysfunction in a dose-dependent manner.
Interestingly, AD is associated with a high prevalence of heart dysfunction in the elderly.
The establishment of heart dysfunction seems to correlate to patient outcome.
Recent studies indicate that cardiomyocyte death was a leading contributor to the development of heart dysfunction.
Both groups with prominent risk for falls had an increased prevalence of heart dysfunction (arrhythmia and ischemic heart disease, respectively).
Similar(43)
Significant factors which appear to play a role in the mechanism of progression of right heart dysfunction include chronic hypoxia, defective calcium handling, hyperaldosteronism, pulmonary vascular alterations, cyclic strain of pressure and volume changes, elevation of circulating TGF- β, and elevated systemic NO levels.
Underlying contributory factors which appear to play a role in the mechanism of progression of right heart dysfunction include chronic hypoxia, defective calcium handling, hyperaldosteronism, pulmonary vascular alterations, cyclic strain of pressure and volume changes, elevation of circulating TGF- β, and elevated systemic NO levels.
Computational modeling and analysis of hemodynamic effects of diastolic heart dysfunction during the whole cardiac cycle.
Computational Modeling and Analysis of Hemodynamic Effects of Diastolic Heart Dysfunction During the Whole Cardiac Cycle.
These markers of right heart dysfunction in the setting of pulmonary embolism portend a worse prognosis [62-64] [62-64]
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