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Effective tolerance-inducing antigen-specific immunotherapeutic strategies hold promise of greater specificity, of lower toxicity and of a longer-term solution to controlling or even preventing RA.
Effective tolerance-inducing antigen-specific immunotherapeutic strategies hold promise of greater specificity, of lower toxicity and of a longer-term solution for controlling or even preventing RA.
In this manner, CD4+T cells of greater specificity were developed by transducing pathogenic CD4+Th1 cells with Foxp3 under the control of IγP, in order to prevent diabetes in NOD mice.
Biomarkers of greater specificity for either CaP or BPH are greatly needed.
The glass spotted oligonucleotide array platform has the potential advantage of greater specificity and has a lower unit cost, but has the lowest coverage of all three platforms.
Thus, measurement of O2 – by DEPMPO spin trapping has the advantage of greater specificity and a lack of perturbation of XDH or XO.
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The higher the extent of enrichment, the stronger is the link between the disease mechanism and the functional category of interest, pointing to greater specificity of the signal.
The difference between the two studies might well be due to greater specificity of the biochemical measures in sub-dissected dentate gyrus compared with the whole hippocampus, as Akt may be differentially phosphorylated by exercise in distinct hippocampal sub-regions.
We opted to use only questionnaire-reported race for consistency and because of the potential for greater specificity.
Further comparative studies are also needed to determine the possible clinical implications of the greater specificity of PET A β seen here.
Furthermore, the sensitivity of rfs-1 animals to IR is relatively weak compared to deficiency in the core HR component BRC-1, whereas sensitivity of rfs-1 and brc-1 animals to crosslinking agents is virtually indistinguishable, in support of the greater specificity of RFS-1/RIP-1 toward stalled replication fork substrates (Ward et al., 2007).
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