Sentence examples for of granular contents from inspiring English sources

Platelet activation also leads to reorganization of platelet cytoskeleton, release of granular contents from dense and alpha granules and finally culminates in integrin activation leading to platelet aggregation [1], [2], [3].

Based on the pathophysiological process of platelet activation by contact with a layer of plasma proteins on the artificial surface and consecutive release of granular contents leading to initiation of thrombi formation [ 11, 26], we used short acting prostaglandin I2 to inhibit platelet activation.

Platelet hyperaggregability and the release of the granular contents of the platelets may contribute to the increased plasma concentrations of 5-HT and 5-HIAA.

Release of the granular contents requires SNARE complexes that consist of the t-SNAREs, syntaxin-4 or syntaxin-2; SNAP-23; and the v-SNAREs, VAMP3 (vesicle-associated membrane protein 3) and VAMP8 [ 13– 16].

Supporting evidence observed in the present study is that further increase in AND type degranulation in the mast cells of the colonic mucosa of the patients with UC-CRS after incubation with SEB implicates that the mast cells have had acute release of the granular contents within a short time in contrast of PMD type degranulation, the chronic release of the granular content [ 36, 51].

Upon tissue injury, however, vascular disruption triggers localised platelet deposition, activation and release of their granular contents.

We propose that myelin-specific CD4 T-cells enter the CNS, and at or near the BBB (blood brain barrier) become activated via interaction with APC via MHC II: self-peptide, resulting in their cell proliferation, cytokine production and the release of lytic granular contents.

Some vacuoles contained one or more small electron-dense masses showing the formation of crystals of hemozoin instead of the dense granular contents (Figure 4C G), indicating that hemoglobin degradation had begun soon after invasion.

NETs are literally net-like structures formed by the mixture of nuclear, cytoplasmic, and granular contents of neutrophils to form a mesh studded with antibacterial molecules.

In particular, a statistically significant increase of intracytoplasmic granular content of dermal MCs was shown in adelmidrol (2% -treated wounds compared to control, thus suggesting the compound is effectively able to down-modulate skin MC degranulation in dogs [ 19].

Therefore the environmental estrogens alone released up to 50% of the releasable granular contents.