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In addition, there was a large reduction in false-positive malaria test results because of good specificity of routine RDTs.
The achievement of good specificity, sensitivity and reproducibility of the analysis depends on the right choice of the phases (e.g. sample pretreatment procedure), the analytical technique and the bioinformatic approach.
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Its ease of use, good specificity, and high-throughput capabilities make it suitable for the application in routine laboratories [11].
RT-PCR or rRT-PCR have played very important role and have been extensively used in infectious diseases surveillance, especially in emergency diseases because of their good specificity, high sensitivity and quick results.
A ROC curve analysis also determined that the capacity of SMILE transcripts to distinguish between operationally tolerant patients and patients with chronic antibody-mediated rejection was also very good, with an optimal threshold of 1.86 (area under the curve [AUC] = 0.83; 95% confidence interval 0.66 to 0.96, good sensitivity of 0.77 and good specificity of 0.75) (Figure S2).
This analysis revealed a very good discriminative power for SMILE to distinguish TOL patients from STA patients with an optimal threshold of 1.23 (area under the curve [AUC] = 0.98; 95% confidence interval 0.95 to 1, good sensitivity of 1 and good specificity of 0.93).
In brief, TssD-5 when used as a single antigen demonstrated the highest sensitivity in both culture confirmed (62%) and IFAT confirmed (85%) samples with an average of 71% and good specificity (96%) with a cut-off value of 0.1094, the lowest amongst the 4 antigens.
According to our results presented in Table 2, it seems that strong expression of CD73 has good specificity (0.85) but low sensitivity (0.63) in the prediction of low risk (pTa) tumors.
This was superior to IMIMs-SDS and demonstrated to be a promising platform for recognition of protein with good specificity.
NO forms quantifiable fluorescent compound with diaminofluorescein (DAF) and allows imaging of NO with good specificity and sensitivity in living cells.
The outcome was that gamma band responses could predict the disruptive effects of ECS with good specificity, leading to the conclusion that gamma mapping could be used to guide ECS during pre-surgical evaluation.
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