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Hepatic tumors appearing after surgery for GIST should therefore be regarded as liver metastases of GIST.
Resourceful as always, she turned once more to the online community of GIST patients.
Finally we provide theoretical as well as empirical validations for the expected properties of GIST 2.0.
These all form part of a modern, multidisciplinary approach to the management of GIST patients.
Our preliminary diagnosis was that both tumors were liver metastases of GIST.
Waterman et al. reported a case of peritoneal dissemination of GIST during surgery [12].
In conclusion, the co-occurrence of liver metastases of GIST and primary HCC is extremely rare.
Distant metastases of GIST arise predominantly in the liver and peritoneum.
Inhibition of this pathway, using the MEK inhibitor PD0325901, reduced the proliferation of GIST primary cells at nanomolar concentrations.
A majority of GIST (63/95) showed mixed (nuclear + cytoplasmic) NTSR1-ir.
However, up to 15% of GIST show weak or negative staining for KIT [4].
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