Sentence examples for of generating single from inspiring English sources

GemSIM, or General Error-Model based SIMulator, is a next-generation sequencing simulator capable of generating single or paired-end reads for any sequencing technology compatible with the generic formats SAM and FASTQ (including Illumina and Roche/454).

A special bubble generator which is capable of generating single bubbles with controllable diameters was devised and incorporated into the separator test.

Perfusion of TTX (1 μM, n = 5; Figure S4C) or riluzole (5 μM, n = 12, Figure 5C) blocked sustained bursts, although riluzole-treated cells remained capable of generating single spikes when depolarized.

Merlin is capable of generating single-point PIBD estimations for many markers, but all such probability calculations rely on accurate assumptions about allele frequencies in a test population.

Their use in mice has been limited [ 59, 60], in part due to the low throughput of transgenesis, and technical difficulties of generating single-copy insertions.

AID deaminates cytosines at immunoglobulin genes on single-stranded DNA thought to be made available during transcription [ 45], however post-fertilisation mouse oocytes are transcriptionally silent [ 46] thus necessitating other means of generating single-stranded DNA substrates.

Furthermore, the use of next-generation sequencing to generate single nucleotide fitness landscapes will offer a resolution that was once only dreamed of (Wright 1932).

Eight tagged libraries were generated, pooled and run on two lanes of a HiSeq 2000 sequencer (Illumina) to generate single reads of 50 bases.

3PFDB is developed as a result of an attempt to generate single PSSM profile for any given protein families.

We identify individual recombination and mutation events, and assess the relative contributions of recombination and mutation in generating single nucleotide polymorphisms (SNPs).

We utilized a series of methods to generate single-cell-derived CSC cultures by combining limiting-dilution assay with cell proliferation assay and the xenotransplantation method.