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Furthermore, a high score corresponds to a high level of functioning on a functional scale, but corresponds to strong presence of symptoms for a symptomatic scale.
The basis for this clinically important difference of 0.03 or greater is that a change in one level of functioning on any of the eight attributes is considered to be qualitatively important [ 34].
In the same vein, patient's self-reported functional capacity assessed using questionnaires based on indicators of functioning on different activities of daily living have been reported in some studies as valid [ 29- 32].
For the single attribute utilities, scores range from 0.0 to 1.0, with a score of 0.0 representing the lowest level of functioning on an attribute and a score of 1.0 representing full functional capacity on an attribute.
Single attribute utility scores for each of the eight attributes range from 0.0 to 1.0, with a score of 0.0 representing the lowest level of functioning on an attribute and a score of 1.0 representing full functional capacity on an attribute.
The availability of such systems, i.e. their probability of functioning on demand, largely depends on their degree of redundancy.
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Analysis of the effect of CaHAM loss-of-function on its own expression showed that CaHAM is negatively autoregulated.
We next investigated the effect of zfBili gain-of-function on zebrafish development.
(B ) Effects of Cnga2 loss-of-function on H2be expression.
(E ) Effects of H2be loss-of-function on odor-evoked electrical responses in the MOE.
Here, we describe the consequences of Trap1 loss-of-function in Drosophila and its gain-of-function on mitochondrial integrity.
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