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We further hypothesized this component would be mathematically modeled and used as an objective developmental index for the study of functional development of the brain.
Our study group consisted predominately of preterm infants, and thus our findings may only be representative of functional development specific to this group.
The Pediatric Evaluation of Disability Inventory (PEDI) is a generic standardised instrument used by the multidisciplinary team for evaluating functional performance, programme monitoring, documentation of functional development and clinical decision-making [ 40].
These results compliment previous investigations that have shown myelination to correlate with various aspects of functional development including the development of language [Aslin and Schlaggar, 2006; Brauer et al., 2011; Pujol et al., 2006], motor skills [Shafir et al., 2008], and reading abilities [Deutsch et al., 2005; Klingberg et al., 2000].
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Our data reveal critical and novel roles for CNTN4/APP in promoting target-specific axon arborization, and they highlight the importance of this process for functional development of a behaviorally relevant parallel visual pathway.
Moreover, Teneurin-3 is required for functional development of orientation-selective RGCs.
Prolactin signals through the Jak2/Stat5 pathway is required for functional development of mammary tissue.
We report here the detailed characterisation of the functional development of human cortical neural networks, together with structural data on the connectivity of those networks.
In particular, as reviewed here, the zebrafish provides access to a circadian timing system that emerges remarkably early during development, a valuable feature for investigation of the functional development of the circadian clock.
Elf5 is a key mediator of structural and functional development of lobuloalveoli [ 47].
The objective of this study was to investigate the impact of genotypic variation on both early microbial colonization of the gut and functional development of intestinal tissue.
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