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Whereas in the linear elastic analyses it represents the point of first yield of the adhesive layer, in the non-linear analyses it represents the point of first failure of the adhesive layer.
Higher overall recoveries were obtained from plates facing the sides of the device, consistent with the point of first failure occurring in the pipe body as observed in previous studies.
Analysis of the crush response is conducted using two methods: (a) Digital image correlation (DIC) to monitor strains and displacement fields in the sample during initial stages of loading and in the vicinity of first failure.
Comparing these locations in both types of analyses show that for the joint designs consisting of one or several plates, J1, J2s and J2r, the point of first yield (Fig. 7a c respectively) corresponds to the point of first failure (Fig. 10a c respectively), and is located at the corners of the loading edge of the adhesive overlap.
For the joint designs consisting in a central joint piece completely surrounding the member, J3s and J3r, the point of first yield (Fig. 7d, e respectively) is located on the loading edge of the adhesive layer, whereas the point of first failure (Fig. 10d, e respectively) is located on the "free edge" of the adhesive layer, i.e. the opposite side from the loading edge.
LRR represent the most frequent type of first failure (14.6%).
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Although our patients did not use the second-generation NNRTI, etravirine (ETR), cross-resistance to this drug was significant in regimens of second failure (31.9%), associated with G190S and M230L mutations.
Time to any failure until re-irradiation was defined as the time from definitive surgery to the time of diagnosis of the first failure.
Time was measured from the start of treatment (radiotherapy and/or chemotherapy) to the time of the first failure or last examination.
Wagner was not alone on the night of his first failure.
Competing risk methodology was used to estimate the cumulative incidence of each first failure type, grade 2 or greater fibrosis, and relapse.
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