Therefore, for the previous hypothesis to be valid, it appears that some form of feedback regulation must exist, whereby AfsS and PhoRP can regulate the transcription of each other.
The PanK isoforms are feedback regulated by CoA thioesters [4], [5], [7], and the loss or alteration of feedback regulation by mutations in PanK result in dysregulated CoA production [5], [8].
It is noteworthy that cholesterol as well as several steroid hormones, including testosterone, progesterone, and estradiol are among the small molecule regulators of this network of genes (Figure 3), suggesting the possibility of feedback regulation between these metabolites and genes involved in their production.
Finally, we present characteristic features for each form of feedback regulation that can aid in their identification.
We perform a systematic analysis of mechanisms of feedback regulation that underlie short-term adaptation in intracellular signaling systems.
We here review selected mathematical models of feedback regulation of fluid transport at the cell scale and identify a general "core shell" structure of such models.
While the semantics can be quite different, biologists and systems scientists use in many cases a similar language (notion of feedback, regulation, etc).
Finally, TTP was observed in crystals of TMPKMtub, locked by Arg14, thus providing a structural explanation for the observed inhibitory effect of TTP putatively involved in a mechanism of feedback regulation of the enzymatic activity.
In this review, we contemplate computer models of oxygenic photosynthesis in the context of feedback regulation of photosynthetic electron transport in chloroplasts, the energy-transducing organelles of the plant cell.
The overall scheme of feedback regulation is shown in Figure 5A.
Interestingly, ARR7 has a negative effect on WUS expression, providing another layer of feedback regulation.
