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There are several types of external messengers.
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In the absence of external stimuli, PTEN generates the messenger phospholipid PIP2 by dephosphorylating PIP3.
In all domains of life, nucleotide-based second messengers allow a rapid integration of external and internal signals into fine-tuned regulatory pathways that control cellular responses to changing conditions.
ECs act as mechanotransducers, whereby the transmission of external forces induces various cytoskeletal changes and activates second messenger cascades, which, in turn, may act on specific response elements of promoter genes.
Lampreys possess seven pairs of external gills.
This is the problem of "external validity".
Networks change because of external events.
Ukraine does have plenty of external debt.
Two types of external solutions were used.
Be aware of external interference.
Reduce the number of external devices.
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