Sentence examples for of existing peptides from inspiring English sources

With this technology, scientists could design and rapidly test new peptides to treat cancer and other diseases, as well as more effective variants of existing peptides, such as insulin, Pentelute says.

Currently, XL-Protein GmbH has 15 preclinical programs listed on their website, six of which appear to be intended as extended-half-life biobetter forms of existing peptides and short protein products (Table  6).

An overview of all the existing peptides and the strategy, design, and utilization of these peptides is given by T. Ebenhan et al. B. Mokaleng et al. report TBIA101, an antimicrobial peptide derivate that was conjugated to DOTA and radiolabelled with Ga for an in vitro and in vivo infection imaging using Escherischia coli-bearing mice by targeting bacterial lipopolysaccharides with PET/CT.

By connecting the native protein termini via a covalent linker and introducing new ends through the cleavage of an existing peptide bond, CP can perturb local tertiary structure and protein dynamics, as well as introduce possible quaternary structure changes.

However, in spite of their potential, many existing peptide and protein drugs (P/P drugs) are rendered ineffective in the treatment because of their inability to deliver and sustainability within the brain.

Previously, we identified anti-cancer bioactive peptide (ACBP), which is such a naturally existing peptide [ 14].

Peptide [Y91]MBP83 99 gave the best cytokine and antibody profile and constitutes a promising candidate peptide for immunotherapy of MS. Structural alignment of existing crystal structures revealed the peptide binding motif of I-As.

Our current study provides a new strategy of utilization of natural existing bioactive peptides, such as ACBP-L used in this study, to potentiate chemotherapeutic effects and minimize toxic effects.

These results underscore the importance of rigorous comparative evaluation of a broad range of existing methods for MHC-II binding peptides prediction methods using similarity-reduced datasets.

Our work joins a small but growing body of existing studies on the use of peptides for OvCa diagnostics.

This study shows that, depending on local conditions, the peptide is capable of existing in at least three states: α-helix, random coil, and β-strand.