Sentence examples for of existing compounds from inspiring English sources
Besides the screening of existing compounds for PFT inhibition, rational drug design has also led to new inhibitors.
As demonstrated by Meredig et al., the formation energy predicted using this model can be compared to the formation energies of existing compounds in order to identify compositions where there is likely a yet-undiscovered compounds.
These results suggest that participants focused more on the separate constituents when reading novel primes than in the case of existing compounds.
The natural precision of these enzymes has been a boon to medicine makers over the decades: chemists have been able to generate new varieties of antibiotic by tweaking the design of existing compounds just enough to fool the enzymes.
The combination of (retro- synthesis retro- synthesisnts of existing compounds leads mainly to synthetically accessible compound prulesand.
While positive examples can be selected from the database of existing compounds, such as PubChem [21] or ZINC [22], no equivalent database is available for negative examples.
Because of the limitations of existing compound collections, this diversity can only fully be exploited using in silico design techniques to guide the selection of molecules with optimal binding properties.
Recent approaches in the area of drug design mainly focus on virtual screening and tautomer enrichment of existing compound databases [2].
The future development of new drugs with novel antibacterial activities requires a detailed understanding of adaptive responses to existing compounds.
These methods have resulted in hypotheses of differential uses (repurposing) for existing compounds that have been validated experimentally.
Despite such diversity, the shared feature of these networks was their high "vulnerability" [ 30] – the propensity for disruption by deletion of any one of the existing compounds.
