The existence of parameter correlations will lead to enormous difficulties in estimating the model parameters.
Fans then, young or old, had little knowledge of the enormous difficulties of baseball at its topmost level, and believed that the heroes on their favorite teams — midsized heroes, by today's measurements — were pretty much like their fathers or older brothers.
Our study highlights some of the enormous difficulties, not all of economic nature, faced by primary health care programmes for chronic diseases in SSA countries.
There are currently numerous clinical trials to investigate the effects of resveratrol on neurodegenerative diseases, of course including AD, in spite of the enormous difficulties [ 29].
But nobody should attempt Chopin's Etudes in public unless they are absolutely sure of their technical command: part of their beauty should lie in the player's joyful mastery of their enormous difficulties.
Rather, their concern was to inform him of the enormous difficulties that lay ahead.
In view of the enormous difficulties faced in reconstructing New Orleans after Hurricane Katrina, or, closer to home, the long delays we have seen in redeveloping the World Trade Center, there were grounds for skepticism.
Although these represent very small numbers of Deaf patients in any one general practitioner (GP) practice, they are important because of the enormous difficulties experienced by Deaf people in accessing healthcare and in communicating with clinicians in consultations.
In the world of control the enormous difficulties encountered in reaching satisfactory results with the design and implementation of controllers for Multi-Input/Multi-Output (MIMO) processes are well known, in particular; when the interactions can not be ignored.
While the massive influx of refugees did pose enormous difficulties, outbreaks of measles and long delays before registration (which permits access to food distributions) should not have occurred.
