Sentence examples for of either pathway from inspiring English sources

PNK is recruited to repair complexes through interactions between its N-terminal FHA domain and phosphorylated components of either pathway.

Co-inhibition of VEGFR and EGFR in preclinical models showed significantly greater antitumor activity over inhibition of either pathway alone, and clinical data support this co-targeting.

Inhibition of either pathway decreased bone metastasis, with no further effect of double blockade.

Molecular blockade of either pathway prevents tumor growth in bone although the effects were not additive.

Induction of Mixl1GFP+ cells in Wnt3a or Activin A stimulated cultures was completely abrogated by inhibitors of either pathway.

We were able to reproduce the ras-enhancing effect (Figure 7B), indicating that a strong activation of either pathway may provoke the enhancement of p53 transcription.

An interesting consequence of independent pathway competition is that fairly small changes in kinetics of either pathway can cause large changes in average cell fate.

Inhibition of either pathway significantly (p<0.01) reduced the expression levels of ERα in C4-HI tumors but not in C4-HD tumors as assessed by western blot (Figure 6A).

Gascoigne and Taylor proposed the independent pathway model by showing that the fraction of cells that slip or die can be altered by perturbing the kinetics of either pathway [7].

Migration/invasion of the NPA cells on Matrigel was also inhibited by stable siRNA knockdown of either pathway, with further inhibition achieved with dual knockdown of the two pathways (Figure 4).

In summary, data obtained with pharmacological compounds suggest that the combined inhibition of PI3 kinase and MEK signaling had the opposite effect when compared to the inhibition of either pathway alone.