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AMG 900 was administered through gavage on days 1 and 2 of each dosing cycle.
Forearm blood flow (FBF) was measured during the final 2 min of each dosing step in both arms, using ECG-triggered mercury-in-silastic strain gauge venous occlusion plethysmography as described previously [ 25].
The heterogeneity of clinical responses might reasonably be explained by the random manipulation of the immune system being determined by mathematical probability when chemotherapeutic regimens are randomly applied without consideration of which particular subsets of susceptible immunological cells are actively proliferating at the time of each dosing.
Individual clinical examinations were carried out immediately post-dosing, and up to the first 30 minutes, and at least twice more during the first 2 hours of each dosing session.
In regard to the end-of-dose phenomenon, regulators usually will advise dense dose sampling especially at the end of each dosing interval.
Subjects returned to the clinic at the end of each dosing period and spontaneously reported adverse events were recorded at every visit.
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The percent Aβ42 lowering of each dosed animal was plotted against the plasma and brain exposures in μM.
Multiple logistic regression was performed to examine the effect of each steroid dosing regimen on respiratory distress syndrome.
The claims are paid from a federal trust fund financed by an excise tax included in the price of each dose of the recommended vaccines.
Usually only a small proportion of each dose is injected.
Aliquots (100 μL) of the appropriate SPA concentrations were dispensed to create eight replicates of each dose concentration.
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