Altogether, these results represent the discovery of three new downstream rewiring mutations on three distinct determinants of specificity (HRD+4, DFG+1, and αD1) and show that single-point NAMs can drive downstream rewiring of a magnitude that is analogous to a new kinase suddenly appearing within the human kinome.
This paper shows that there are two distinct determinants of the survival and maturation of transplants into the adult dentate gyrus from two neurogenic regions of the brain.
References. 1. Garland A, Olafson K, Ramsey CD, Yogendran M, Fransoo F; Distinct determinants of long-term and short-term survival in critical illness; Intensive Care Med 2014, 40, 1097 1105.
In short, one can distinguish at least three distinct determinants of protein half-life.
Thus, these two studies identify essential and distinct determinants of mammary acini polarity.
The analysis showed that gestational age and birth weight contributed to 10%and13%3% of the variation, respectively, being two distinct determinants.
The epitope expression of PEMs isolated from either source is also similar, with both bearing topographically distinct determinants for several anti-mucin MAbs.
Among homosexual men, non-adherence and unsafe sex were not correlated and had distinct determinants.
The purpose of the study was to compare the impact of distinct socio-cultural determinants such as the regional environment and selected parental characteristics on adiposity, PA and motor skills in preschool children.
Six studies assessed the determinants of distinct depressive trajectories among adults, with many examining the influence of socioeconomic circumstances.
