Sentence examples for of discrete clocks from inspiring English sources

Local clocks are therefore a special case of discrete clocks.

Genetic algorithms appear to be well suited for optimizing the allocation of discrete clocks but their efficiency in the local clock problem is arguable, probably due to the different solution encodings.

Although root age estimates under local and discrete clocks are similar, the relaxed (UCLN) and the discrete clock failed to recover the rate shift pattern that Drummond and Suchard [ 9] first identified using a random local clock.

The substitution rate and tMRCA were estimated under a GTR + Γ4 substitution model using strict and discrete clocks with Physher.

Given a fixed number of rate classes, the encoding of each individual of the GA in the discrete clock model is represented as vector of size N where each element represents the class assignment of a branch.

The number of combinations for the discrete clock algorithm is also computationally difficult and warrants the use of approximation methods.

One solution to search the high-dimensional parameter space of the local and discrete clock models without using an MCMC is to use a genetic algorithm (GA).

Similarly, we present a GA to determine the number and allocation of rate categories under a discrete clock model (GADC).

The likelihood of this parameter rich non-clock model will give us an upper-bound for the likelihood of the global, local and discrete clock models.

We analysed 50 replicates of each scheme using Physher with a strict, local, and discrete clock and the confidence intervals of the root were derived for the root age using the methods described previously.

The local clock model recovered the true root age in every replicate simulated with a local clock and it recovered the true root age in 49 of 50 replicates simulated under a discrete clock model.