Although we considered perfect detection of symptomatic cases upon symptom onset during quarantine in the main text, here we examine the sensitivity of the effectiveness of quarantine to differing efficacy of case detection.
The lower protective efficacy during the entire study period (24.8%; 95% CI 14.3 34.0) [4] is therefore a consequence of the prolonged periods between IPT doses, rather than differing efficacy of each dose of IPTi.
In the short-term period after IPT, however, the existing infection might be considered as the more likely cause of malaria, given the resistance patterns in Navrongo at the time and differing efficacy of SP as a therapeutic and prophylactic agent (discussed below) [24].
Although there are several migraine therapies and medications currently available to treat migraine, most of them work with differing efficacy and are often associated with adverse effects [20].
A plausible explanation for the differing efficacy of internal and external application on eCBmGluR is that the DAGLα responsible for eCBmGluR is much less accessible to externally applied inhibitor.
These results provide a mechanistic basis for the differing efficacy of VX-770 in patients carrying G551D and ΔF508 CFTR and have important implications for the design of assays for small molecule screening.
Currently, there are five anti-TNF agents approved that are equally effective in the treatment of rheumatoid arthritis but exhibit differing efficacy in other inflammatory conditions.
Given possible data pointing toward differing efficacy by line of chemotherapy, analysis was stratified into second-line trials and trials investigating third-line (or later) setting.
Although both antagonists are dihydropyridines, they have differing efficacy based on their structural differences [ 27].
This goes on to show that the inclusion of the categorical feature indicating the type of region, namely, 3' UTR, CDS, or 5' UTR, is able to explain the differing efficacies of target sites in different regions, and that other features like thermodynamic binding, accessibility, conservation, etc., have the same predictive power in the three different regions.
