In reality, according to three later analyses of Ankrah's study, the primary reason for the decline was completely different: substantial numbers of Ugandans had ended affairs and remained faithful to one partner.
While the consensus network identified most pathways, known to be related to glioma, the comparisons of different tumors revealed substantial differences in the activities of crucial signaling cascades.
By comparing ESTs we detected multiple copies of different genes with substantial variation in synonomous and, in certain cases, non-synonomous sites as well, while confirming that multiple gene copies were expressed [10], [17].
Despite a growing number of reported positive genotype phenotype associations across a variety of different diseases, a substantial proportion of these associations lose significance when tested in different patient populations, casting doubt on whether the association truly exists or merely represents a chance finding [ 7].
The use of different approaches leads to substantial differences in study results and thus limits the comparability of findings, and makes interpretation difficult.
Transcriptional profiles of different brain regions show substantial differences [ 27, 29], making comparisons between profiles derived from various brain regions difficult.
In contrast, the multiple isolates of the sexual species E. typhina displayed higher levels of variation, as is further supported by possession of different MT genes and substantial differences between mitochondrial genomes [ 24, 30].
For example, a study of enalapril formulations found considerable variation in the stability of different preparations, leading to substantial differences in drug concentration and drug-release profiles between the reference and generic formulations [ 90].
Our studies across a range of different tumour models showed substantial heterogeneity in tumour IFP, suggesting differences in the vascular development and interstitial fluid dynamics in the individual tumours.
The guts of different individuals have a substantial overlap in terms of species composition and function because it was always thought that human gut flora was very variable".
