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Once Tregs are induced, numerous mechanisms (see Sections 4-iv, 4-v, 7-iii) exist allowing small numbers of Tregs of one specificity to expand, outgrow, convert non-Tregs of different specificities to suppressive function (infectious tolerance), and also non-specifically suppress responses to other antigens (bystander suppression) [93].
Antibodies of the human IgG4 subclass uniquely undergo a process of Fab-arm exchange in which the heavy-chains of antibodies of different specificities can dissociate and then recombine.
Antibodies (Abs) of different specificities can assemble identical VL domains with different VH domains.
Again, trees could be built with a sample of tRNAs of different specificities.
Anti-retinal autoantibodies of different specificities have been liked to AR and CAR.
It is possible that diversification of different specificities occurs by changes at different sites in different lineages.
Similar(41)
We agree that this can be interpreted as an indicator of different specificity, but we cannot estimate the depth of this difference.
We have extended this approach to the blocking of multiple epitopes simultaneously, which led to the recovery of new antibodies of different specificity, including one new neutralizing activity.
Moreover, laboratory tests for the determination of 12-LOX and PAI-1 used antibodies of different specificity.
Characterization of secreted PAPP-A in CMs was performed by EIA using capture antibodies of different specificity but with the same HRP-conjugated capture antibody.
Besides PPRs, a variety of additional factors of different specificity have been described that execute processing steps left over by PPR proteins [ 39- 41].
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