13 A total of 50 items were included in the questionnaire (excluding demographic and social economic characteristics), which yielded a Cronbach's α of 0.847 and a Spearman-brown formula of 0.884, demonstrating acceptable internal reliability and validity.
Fitting the models to the test dataset resulted in a similar pattern of results but poorer model fit with none of the models demonstrating acceptable calibration and lower AUC than the training dataset models (Table 5).
Of the 141 GSE surveys, 13 (9.2%) failed to demonstrate acceptable goodness-of-fit to the Rasch model in the 10-item version, indicating that the response patterns of these persons were unlikely given their underlying level of general self-efficacy.
This proportion was reduced slightly as the misfitting items were removed, with the 7-item GSE having 8 respondents (5.7%) failing to demonstrate acceptable goodness-of-fit.
Cleaning validation programs are developed to demonstrate acceptable carryover of drug substances/products when multiple drug substances are manufactured in shared process equipment.
A Kalpha coefficient of 0.88 demonstrated acceptable inter-rater reliability between the scores of the two skills lab teachers.
A customized software program provided two additional assay metrics, Quantification Titer (QT) and Threshold Titer (TT), both of which demonstrate acceptable accuracy, precision and dilutional linearity.
Early-phase clinical studies of tremelimumab demonstrated acceptable toxicity (diarrhoea/colitis, dermatitis, fatigue, pancreatitis, Grave's disease) and similar efficacy of 10 mg/kg monthly and 15 mg/kg quarterly doses of the antibody [ 57] with median survival of 10.3 and 11 months, respectively [ 58].
The figures from these studies, and another study using a different child health instrument [ 29] showed low parent-child agreement in all domains of health, A recent literature review on HRQOL instruments in children [ 30] found 13 generic instruments with self- and parent-reported versions, and only 6 of which demonstrated acceptable psychometric properties.
The five specific aims of the testing project will result in production of a well-characterized, tested set of controls with demonstrated acceptable performance on major microarray platforms and commonly used QRT-PCR methods.
