Since degeneration of cartilage is one of the decisive steps in OA development, dysfunction and disturbed control of mediators influencing cartilage metabolism following different pathologies of the ankle may be hypothesized [ 3].
Disruption of an interhelical salt bridge between the retinal protonated Schiff base linked to H7 and Glu113 on H3 is one of the decisive steps during activation of rhodopsin.
Aberrant change in the Runt-related transcription factor 2 (RUNX2) mediated signaling cascade is one of the decisive steps during the pathogenesis of fluorosis.
TOKYO — Japan said Friday that it would seek to phase out nuclear power by 2040 — a historic shift for a country that has long staked its future on such energy, but one that falls far short of the decisive steps the government had promised in the wake of the world's second-largest nuclear plant disaster last year.
Having quickly assembled his cabinet, in January he announced a ¥10.3 trillion fiscal stimulus.This was the first of three decisive steps.
But no one could explain how the microbes prompt this dramatic transformation, one of the most decisive steps in the animal's life cycle.
One thing Andras Schiff is showing in his Carnegie Hall traversal of the sonatas, played in the order Beethoven composed them, is that a handful of relatively small but decisive steps lead from the Haydnesque playfulness and Mozartean elegance of the earliest works to the grand proclamations — sometimes elevated, sometimes brash — of the mature ones.
She said it was "up to the government of Pakistan to take decisive steps in the days ahead" against militants, but did not give any details.
"We will do our part," she said in remarks at the American Embassy here, "and we look to the government of Pakistan to take decisive steps in the days ahead".
In other words: we do not, as yet, have an adequate response mechanism, an ability to eliminate the threat of terrorism the way decisive steps undertaken by the British SAS, the German GSG-9 and other units succeeded in reducing the number of cases involving hijacked aircraft to almost nil.
