For increased efficiency, advantage was taken of the constrained size of the data domain: only a single request is sent to the database backend to fetch the entire set of available genes.
The constrained size of viral genomes, along with the increasing yield of sequencing instrumentation and methods, have combined to give researchers extremely high rates of coverage when sequencing viral genomes using this approach.
The ligand binding site is characterized by a constrained size of the cavity and the requirement for both an acidic group and a hydrophobic group in the ligand (Fig. 3C).
Shortening the CTG tract from 22 to 16 repeats reduced expansions by two-thirds relative to (CTG 22 and also showed a more constrained size distribution of +6 to +14 repeats.
The constrained size and weight, the appropriate focus on extreme levels of reliability, and the need to be efficient over a wide range of operating conditions suggest that the ship will lead the development with the land-based system following.
In our analysis of the ENCODE regions, we choose a prior expectation of 8% of constrained sequences and the expected constrained element size of 12 bp which limit the bases called on bootstrapped AR alignments to<0.5%.
As a matter of fact, we allowed for a wide range of GC content (corresponding to melting temperatures of 57 to 65 °C) but strongly constrained amplicon size differences to a maximum of 200 bp (but actual size differences were much less for most amplicons, see Additional file 2 : Figure S1).
Metamorphosis can thus be seen as a way to decouple traits between life stages, although the performance of froglets remains somewhat constrained by size, which is determined in, and is carried over from, the tadpole stage.
For 2 of 11 VOCs (1,4-dichlorobenzene and tetrachloroethylene), between-child variability was greater than within-child variability, a condition that tends to complicate efforts to distinguish differences between individuals with a limited number of measurements and a constrained sample size.
In an era of constrained news media budgets, they aren't cutting a lot of corners.
