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Patients who died were excluded because of the absence of complete adherence information.
Furthermore, the increased likelihood of complete adherence was associated with a 25% decrease in the rate of hospitalisation.
Thus, multiple-pill regimens were associated with lower rates of complete adherence and correspondingly higher overall healthcare costs.
Neovascularisation of the matrix occurs during the early stages of complete adherence of ADM to the recipient wound bed [ 47].
The primary results did not change under a hypothetical scenario of complete adherence to treatment (allocated insoles worn daily for a year by every patient).
In summary, our nationwide study provides strong and consistent evidence that daily changes in ambient O3 exposure are linked to premature mortality, even at very low pollution levels, including an idealized scenario of complete adherence to current O3 regulations.
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This is a crucial point for both the correct classification of CD and related patient management in view of the recent data showing the persistence of villous atrophy in spite of the complete adherence to GFD [ 9, 10].
By 6 months of age, complete adherence was defined as having had at least 3 well child visits; 2 visits between 6 and 12 months; 2 visits between 12 and 18 months; and one visit between 18 and 24 months (Table 2).
Microbiological tests were significantly (p<0.001) more frequently requested in the group of patients with complete adherence versus those with non-adherence (Table 2).
In the present study the group of patients with complete adherence to recommendations showed significant higher clinical success and eradication among microbiologically evaluable patients.
The percentage of smokers (23.6% versus 13.4%, p=0.006) and of patients with chronic respiratory insufficiency (45.2% versus 32.9%, p=0.009) was non-significantly higher in the group of patients with complete adherence versus non-adherence.
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